Our work is funded by R&D&i projects PID2020-115961RB-C31, PID2020-115961RB-C32 and PID2020-115961RA-C33, financed by the Spanish MICIU/AEI/10.13039/501100011033/.
We aim to uncover the fundamental mechanisms governing cerebrospinal fluid (CSF) dynamics in the human central nervous system. Combining the tools of fluid mechanics—mathematical modeling, computational simulations, laboratory experiments—with in-vivo MRI imaging we seek to:
Explore novel intrathecal drug delivery strategies
Unravel the role of glymphatic flow in neurodegenerative conditions
Deepen our understanding of diseases such as syringomyelia and hydrocephalus
We are a multidisciplinary team of engineers and scientists from leading universities in Spain and the USA.
Our group combines expertise in fluid mechanics, biomedical engineering, numerical methods, and medical imaging to tackle real-world challenges related to CSF flow and neurological health.
This infrastructure allows us to validate models, test devices, and generate clinical-relevant data under controlled conditions.
for physical modeling and flow visualization
including 3D printing and custom flow circuits
for precise flow measurements
in image segmentation and quantitative CSF flow analysis
for in-vivo CSF flow imaging
for numerical simulations and data analysis